Selected acute phase protein in the diagnosis of late allergic response and the development of tolerance in food allergy

Background Food allergy as an immunological disorder leads to specific local and general inflammation. There are no confident tests to confirm the diagnose of late reaction of food allergy or developing tolerance. Acute phase proteins (app) are markers of inflammation even localized or of very low intensity and their modulator effect on the immune reaction was proved in many studies. Since antichymotripsine (ACT) influences processes of induction, cells’ migration and effector mechanisms of allergic reaction we studied the usefulness of estimation of ACT level and its glycosylation profile (W1,W2, W3, W4 glycoforms) in diagnostic process of food allergy/ tolerance in children.